Article Outline: Ischemic Ventricular Fibrillation: The Importance of Being Spontaneous by Ouyang et al.

I outline the bits of papers I find interesting for reference. I’m going to try posting some of these outlines in the hopes that someone finds them useful. It’s very easy for me to export them from FreeMind. The article is Ischemic Ventricular Fibrillation: The Importance of Being Spontaneous(Cite-U-Like) by Ouyang et al.

Ouyang 1981

  • Ischemic Ventricular Fibrillation: The Importance of Being Spontaneous
  • Authors
    • Ouyang, Pamela
    • Brinker, Jeffrey
    • Buckley, Bernadine
    • Jugdutt, Bodh
    • Varghese, Paul
  • Topics
    • defibrillation threshold
      • spontaneous vs. induced VF
      • regional ischemia vs. normal
  • Parameters
    • n = 10
    • canine
    • occlusion
      • sites
        • around LAD just distal to first septal perforator artery
        • midway along LAD in anterior interventricular groove
        • around left circumflex coronary artery near its origin
      • duration
        • 10 min or until spontaneous vfib
      • DFT measured if reperfusion fib occurred
    • vfib
      • induced by current during t-wave
      • allowed to continue 10s
    • defib
      • electrodes
        • venous catheter where VC meets right atrium
        • apical cup
      • waveform
        • trapezoidal with exponential delay
        • 1-30 watt seconds with increments
          • Progressively increased until DFT reached
          • 1
          • 2
          • 5
          • 15
          • 20
          • 25
          • 30
      • DFT
        • lowest energy that successfully defibrillated
        • no change noticed over two minutes
        • determined for every episode of fib
    • data on extent of ischemic zone
      • mass of risk region for each occlusion
      • percent of LV mass in risk region
  • Notes
    • vfib episodes
      • 32 induced in normal hearts
      • spontaneous vf in 13/25 ischemic episodes
      • induced vf in 12/25 ischemic episodes
      • 19/25 reperfusions resulted in vf
        • 12/13 instances of occlusion w/ sponteneous vfib
        • 7/12 instances of occlusion w/ induced vfib
    • difference b/w DFT in spontaneous vs. induced fib not related to mass of occluded bed
  • Conclusions
    • when ischemia was present, DFT rose significantly
    • DFT greatest in ischemia when vfib spontanous
    • DFT twice as high for spontaneous (vs. induced) vfib