Article Outline: Mapping of left ventricular blood flow with radioactive microspheres in experimental coronary artery occlusion by Becker et al.

Outline below the fold…

Becker 1973

  • Mapping of left ventricular blood flow with radioactive microspheres in experimental coronary artery occlusion

    Authors

    • Becker, LC

    • Ferreira, R
    • Thomas, M

    Topics

    • radiomarking

    • morphology of infarction

    Parameters

    • 15 micron microspheres

    • n = 10
    • dogs
    • LAD occlusion
      • silk ligatures

      • all major FW diagonal branches (3-5)
      • branches rather than main vessel to reduce immediate mortality
    • FW cut into strips 1-2 cm wide, apex-base
    • epi/endo divisions made
    • 30-60 minutes post-occlusion

    Notes

    • margins of cyanosis sharp at basal and lateral aspects

    • maximal flow reduction in center of lesion
    • concentric areas of intermediate flow
    • region of hyperperfusion around infarct
      • possibly artifact of method?