Article Outline: Internal Cardiac Defibrillation Threshold: Effects of Acute Ischemia by Jones et al.

This was kind of interesting, but it doesn’t show very much. The main conclusion that I got from it was that large regions of coronary occlusion lead to death within 30 minutes, but I don’t think that’s really what they were trying to find or show.

The Cite-U-Like page is here. The rest is below the fold.

Jones 1986

  • Internal Cardiac Defibrillation Threshold: Effects of Acute Ischemia
  • Authors
    • Jones, Douglas
    • Sohla, Anand
    • Klein, George J.
  • Topics
    • internal DFT
    • lead orientation
    • acute ischemia 1B
  • Parameters
    • n = 30
      • 15 normal
      • 15 occluded
    • pigs
    • distal 1/3 of LAD ligated
    • began investigation 30 min post-ligation
  • Notes

    • Figure 1: Dotted area reperesents ischemic zone produced by ligation of distal LAD

      significant improvement in number of successful defibs using an epicardial plaque (vs. transvenous catheter) [duh]

      Regardless of electrode configuration, no difference in success b/w normal and acutely ischemic pig hearts

      relatively small and distinct ischemic zone produced by ligation of distal third of the left anterior descending artery

      • larger insults resulted in death
  • Conclusions

    • Regardless of electrode configuration, no difference in success b/w normal and acutely ischemic pig hearts

      Key: SMALL ISCHEMIC ZONES don’t affect DFT