This was kind of interesting, but it doesn’t show very much. The main conclusion that I got from it was that large regions of coronary occlusion lead to death within 30 minutes, but I don’t think that’s really what they were trying to find or show.
The Cite-U-Like page is here. The rest is below the fold.
- Internal Cardiac Defibrillation Threshold: Effects of Acute Ischemia
- Jones, Douglas
- Sohla, Anand
- Klein, George J.
- internal DFT
- lead orientation
- acute ischemia 1B
- n = 30
- 15 normal
- 15 occluded
- distal 1/3 of LAD ligated
- began investigation 30 min post-ligation
- n = 30
Figure 1: Dotted area reperesents ischemic zone produced by ligation of distal LAD
significant improvement in number of successful defibs using an epicardial plaque (vs. transvenous catheter) [duh]
Regardless of electrode configuration, no difference in success b/w normal and acutely ischemic pig hearts
relatively small and distinct ischemic zone produced by ligation of distal third of the left anterior descending artery
- larger insults resulted in death
Key: SMALL ISCHEMIC ZONES don’t affect DFT