Outline below the fold…

Becker 1973

• Mapping of left ventricular blood flow with radioactive microspheres in experimental coronary artery occlusion

  Authors

  • Becker, LC
  • Ferreira, R
  • Thomas, M

  Topics

  • radiomarking
  • morphology of infarction

  Parameters

  • 15 micron microspheres
  • n = 10
  • dogs
  • LAD occlusion
    • silk ligatures
    • all major FW diagonal branches (3-5)
    • branches rather than main vessel to reduce immediate mortality
  • FW cut into strips 1-2 cm wide, apex-base
  • epi/endo divisions made
  • 30-60 minutes post-occlusion

  Notes

  • margins of cyanosis sharp at basal and lateral aspects
  • maximal flow reduction in center of lesion
  • concentric areas of intermediate flow
  • region of hyperperfusion around infarct
    • possibly artifact of method?